STATE-DEPENDENT METABOLIC PARTITIONING AND ENERGY CONSERVATION: A THEORETICAL FRAMEWORK FOR UNDERSTANDING THE FUNCTION OF SLEEP.

State-dependent metabolic partitioning and energy conservation: A theoretical framework for understanding the function of sleep.

Metabolic rate reduction has been considered the mechanism by which sleep conserves energy, similar to torpor or hibernation.This mechanism of energy savings is in conflict with the known upregulation (compared to wake) of diverse functions during sleep and neglects a potential role in energy conservation for partitioning of biological operations b

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Enhanced Extraction of Blood and Tissue Time-Activity Curves in Cardiac Mouse FDG PET Imaging by Means of Constrained Nonnegative Matrix Factorization

We propose an enhanced method to accurately retrieve time-activity curves (TACs) of blood and tissue from dynamic 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) positron emission tomography (PET) cardiac images of mice.The method is noninvasive and consists of using a constrained nonnegative matrix factorization algorithm (CNMF) applied to the matrix (

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Hybrid design of optimal shunt capacitor allocation and reconfiguration of radial distribution systems considering techno-economic benefits

Efficient power delivery is crucial for power distribution systems, prompting utilities to consistently seek out new technologies to improve their performance.Managing power loss and cost efficacy stands out as a critical concern, directly impacting systems efficiency.Hence, this study provides an innovative method for the performance enhancement o

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Structural and Functional Neural Correlates of Anorexia Nervosa

The findings from neuroscience have shaped our understanding in the past decade regarding the way we perceive psychiatric illness.In addition to the more conventional theories that are based solely on the psychological and sociocultural factors to explain psychiatric disorders, there is growing evidence supporting a multifactorial etiology with gen

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